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Myositis ossificans progressiva(MOP) is a rare, slow progressive autosomal dominant disorder that principally affects children under the age 10 years. It is characterized by progressive fibroblastic proliferation, and subsequent calcification and ossification of subcutaneous fat, muscles, tendons, aponeuroses and ligaments. The disorder is often associated with symmetrical malformations of the digits, especially microdactyly or adactyly of the thumbs and great... |
